2025年 新着論文 9 糖尿病診療分野から論文が発表されました
Plantar pressure and shear stress during gait in people with diabetic neuropathy
- PMID: 40166448
- PMCID: PMC11954732 (available on )
- DOI: 10.1007/s13340-024-00789-4
Abstract
Aims: Diabetic foot ulcers are a leading cause of lower extremity amputations, significantly affecting the quality of life. Excessive plantar surface pressure and shear stress are key factors in ulcer development and aggravation. This study aimed to determine the association of these forces with the progression of diabetic peripheral neuropathy to help in foot-ulcer treatment and prevention.
Methods: Participants were categorized into four groups: individuals with no diabetes (NS), people with diabetes without peripheral neuropathy or foot-ulcer history (DM), those with diabetes with peripheral neuropathy but no foot-ulcer history (DPN), and people with diabetes with active or past foot ulcers (DFU). Plantar pressure and shear stress were measured during walking.
Results: The study included 47 participants. The DFU group demonstrated significantly higher pressure peak value and plantar pressure time integral value at the fifth metatarsal head compared to the DPN and DM groups. The DPN group exhibited significantly higher shear-stress time integral and shear stress time compared to the NS group.
Conclusions: In the DPN group, an increase in shear stress was observed. In the DFU group, an increase in plantar pressure and a tendency for an increase in shear stress were noted. Further research is needed to understand how these changes trigger the onset of foot ulcers.
Supplementary information: The online version contains supplementary material available at 10.1007/s13340-024-00789-4.
Keywords: Diabetic foot ulcer; Diabetic neuropathy; Gait analysis; Plantar pressure; Shear stress; Type 1 or type 2 diabetes.
© The Japan Diabetes Society 2025. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
Conflict of interest statement
Conflict of interestMunehide Matsuhisa has received lecture fees from Abbott Japan, Sanofi, Sumitomo Pharma, Novo Nordisk Pharm, Terumo, Eli Lilly JP, Kyowa Kirin, Boehringer Ingelheim, and Origuru Therapeutics. In addition, he has received research funding from the Japan Association for Diabetes Education and Care. Ethical aprroval All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (the Ethics Committee of Tokushima University Hospital / 2021/6/28 / 4012) and with the Helsinki Declaration of 1964 and later versions. Informed consent or a substitute for it was obtained from all participants for being included in the study.
